Tadhg Furlong, Jamison Gibson-Park, and Cian Healy of Leinster have been ruled out of Ireland’s crucial Six Nations match against France on Saturday.
Furlong missed Ireland’s opening-day win over Wales due to a calf injury.
Scrum-half Gibson-Park as well as prop Healy was a late withdrawal from the Cardiff matchday squad due to hamstring injuries.
After being forced off in the second half in Cardiff, captain Johnny Sexton will have an HIA on Monday.
France visit Dublin on Saturday after a narrow victory over Italy in Rome, while Ireland dominated Warren Gatland’s Wales at the Principality Stadium.
Conor Murray took Gibson-place Park’s in the starting XV ahead of the game, and Craig Casey was moved to the bench.
Dave Kilcoyne was named as a replacement for Healy against Wales.
Caolin Blade, Connacht scrum-half, and Leinster loosehead prop Michael Milne has joined Andy Farrell’s team in Dublin.
Ulster hooker Tom Stewart and Munster’s Roman Salanoa have both been called up ahead of the Wales game.