Bangladesh won the series by four wickets over England in the second T20 international in Mirpur.
After six overs, England were 50-1, but a flurry of wickets followed on a difficult, turning pitch, and the tourists were bowled out for 117 in the 20th over.
Ben Duckett led the middle order with 28 runs from as many balls, but he lost four partners to Mehedi Hasan, who finished with figures of 4-12.
Bangladesh advanced steadily in their chase, with Najmul Hossain Shanto’s unbeaten 46 bringing them home with seven balls remaining.
Jofra Archer took two wickets late in the game, finishing with an impressive 3-13, but the hosts took 15 off the first five balls of Chris Jordan’s penultimate over.
On Tuesday, the series concludes with a final dead rubber at the same venue.
England were already dealing with the absences of a number of key batters, including Ben Stokes, Alex Hales, and Will Jacks, in their first series in this format since winning the T20 World Cup in November.
After losing the first match of the series on Thursday, captain Jos Buttler decided to make more changes to the winning formula, dropping himself to four and promoting Dawid Malan to open, while also giving 18-year-old prodigy Rehan Ahmed his debut.
Malan was bowled cheaply by Taskin Ahmed, and Buttler was bowled for four by Hasan Mahmud’s yorker as England were reduced to 57-4 after nine overs.
Duckett has provided some resistance as others fell around him in successive games, but has failed to kick on after reaching his twenties.
He and Sam Curran put on a 34-run partnership in the middle overs, overcoming a difficult pitch and some excellent bowling from Mehedi, who claimed Curran as one of two stumping victims.